This study presents the multifunctional roles and specific beneficial effect of giving three levels of lactoferrin protein on hematological parameters in karadi male lambs after weaning, 16 Karadi male lamb were utilized, 3 months old, with an average live weight of (21±0.41 kg), Male lamb were partitioned haphazardly and similarly to four groups (control, Treatment 1 were given (500 mg LF per week)Treatment 2(1000 mg LF per week) Treatment 3(1500 mg LF per week)for each lamb, dosing capsules by 500 mg oral dose until the end of the experiment. Some blood parameters, proteins, and enzymes in the serum were analyzed results showed a significant increase (P>0.05) in Hb concentration on the period 3 of the study in the third treatment group (13.550 gm/dl) comparing to the lambs of the control group (11.650 gm/dl). lambs of the third treatment group on the period 3 showed a significant (P>0.05) increase in RBC (3.890 ×1012/L) as compared to the control group lamb(2.670×1012/L), the first treatment group on the period 2 showed a significant (P>0.05) increase in WBC (11.890×106 cells/ml) as compared to the control group lamb (9.125×106 cells/ml).