Authors
Department of Horticulture and landscape gardening, College of Agricultural Engineering Sciences, University of Baghdad, Baghdad, IRAQ.
,
Document Type : Review Paper
Abstract
The name Atropa is thought to have been derived from the Greek goddess Atropos while, meaning a beautiful lady. Belladonna has also been used over the past centuries to relax muscles, especially of the stomach and intestines, to help relieve intestinal colic, and to treat peptic ulcers. It also relaxes the urinary tract, removing spasms. The ancients used the plant to treat Parkinson's disease, as it works to reduce tremors and stiffness. Modern medicine proved that belladonna alkaloids inhibit the parasympathetic central nervous system that controls the various involuntary activities of the body. These alkaloids increase heartbeats. It has been shown that belladonna is a sedative used to remove the pain of diseases accompanied by bouts of muscle contractions.
- Spiegl , F.and Fritz ,.1996. sick nots An Alphabetical Browsing –Book of Derivatives Abbreviations, Mnemonics and slang for Amusement. Washington, DC: Taylor & Francis, pp. 21-22. ISBN 1-85070-627-1.
- Al-Degwi, Ali. 1996. Encyclopedia of Medicinal and Aromatic Plants, Madbouly Library, Atlas Press (Book Two).
- Kayqon . 2008. Edible fruits in a cool climate the evalution and ecology of endozoochory in the european flora.In: furit and seed production : Aspects of development , Environmental physiolog and ecology (Society for Experimental Biology seminar series) Cambridge , UK: Cambridge university press pp. 240.
- Genovae, , K. G. and Y. Beeva. 1997. ((Study on the germination of Atropa belladonnd L.seeds))(PDF) .Bulgarina Journal of plant physiology 23(1-2 ) : 61-66.
- Wilson , J., Heather . 2008. Buzzed the straight facts about the most used and abused drugs from alcohol to ecstasy ,New York city : pp.107.
- 2010. Alternative medicine, treatment with herbs and medicinal plants. Translated by Dr. Omar Al-Ayoubi, supervised by Dr. Muhammad Debs, p. 66
- 2007 . (( Solanaceae IV : Atropa belladonna ,Deadly night shade )) (PDF) .J R Coll physicians Edinb 37 (1) : 77 – 84.
- Qutb, Taha Fawzi Hussein.1979. Medicinal plants and their components. P. 133:137.
- Verpoot ,R .and A.W.Alfermann .2000. In metabolism engineering of plant secondary metabolism, kluwer. Academic publishers, pp. 3-8.
- Ramawat , K.G. 2004. Plant biotechnology. Printed in New Delhi.India.p :50-62.
- Taiz,L. and E.Zeiger . 2006. Plant physiology. Sinauer assciates, Inc. Publishers. Sunderland.
- Kinghorn, A. D. and, M. F. Balandrine (EDS). 1993.Human medicial agents from plant ACS Symposium series 524 , Washington.
- Al-Shahat, Nasr Abu Zaid. 2006. Physiology and chemistry of alkaloids in medicinal plants and their pharmacological and therapeutic importance, Scientific Book House for publication and distribution, Cairo.
- Al Nuaimi, Dr. Jabbar Hassan 2010. Treatment of fruit trees and shrubs and forests, p. 13:15.
- Saidon ,N. A . 2008.The establishment of embryogenic callus culture of Hyoscyamus niger and the detection of hyoscyamine in the culture –University sains Malaysia.
- Sarin, R., .2005 . Useful metabolites from plant tissue cultures biotechnology 4 (2) : 79-93. University of Rajasthan , Jaipur , India.
- Dale ,M.1999.The extra pharmacopoia -31 Edition.
- Laurence , D.R ,P.N. Bennett and M.J. Brown. 1997.Clinical pharmacology . 8 th edition . Churchill Living stone.
- Pepeu ,G.and ,M.Grazia .2004. Acetychline: I Muscarinic Receptors. In Gernot Riedel ,Bettina platt. From messengers to molecules :memories are made of these (illustrated ed.) .springer.ISBN 030647825, 9780306478628.
- Clark , W . G . , D .C. Brate . and A. R. Johnson. 1988. Goths medical pharmacology , 2 ed . the C.V . Mosby company , ST Louis .Washington D .C. Toronto.
- George ,E .F, M.A.Hall, and G.J.Klerk . 2008 .Plant propagation by tissue culture practices . 3rd edition . Part plant growth regulators . Auxins their analogues and inhibitors , pp 175 , 185 , 186 .
- Kurs, W.G.W., and F. Constable, .1997.Production of secondary metabolities . In " Biotechnology in Agriculture ".(A. Aerman) .pp.1-42, marcel Dekker.
- Kutney, J .P., 1997 .Plant cell culture combined with chemistry –routes to clinically important compounds Pure & Appl. Chem. .Vol .69 ,No. 3,PP.431 -436.
- Sateesh , M.K. 2003. Biotechnology -5. New age International publishers.
- Saxena , P.K. 2005. Plant cell technology laboratory . University of Guelph , Kluwer Academic press department of plant Agriculture.
- Nalawade , S. and H.S.Tsay . 2004.In vitro propagation of some important Chinese medicinal plants and their sustainable usage ,In vitro cellular and Development Biology - plant volum 40 , Number 2 , pp . 143- 154 (12) .
- Moreno , P .R . H., V. D. Heijden , and R. verpoote ,. 1993. Effect of terpeniods precursor feeding and elicitation on formation of indole alkaloids in cell suspension cultures of Cathranthus roseus Plant cell reports, 12: 702 -705.
- Whitmer , S., C. Canel, D . Hallard , C . Goncalves and R .Verpoote ,. 1998 . Influence of precursor availability on alkaloids accumulation by trans-genic cell line of Cathranthus roseus , plant Physiology , 116 :853-857.
- Silvestrni , A., G . Pasqua , B. Botta, B. Monacelli , vander Heijden, and R. Verpoote ,. 2002. Effect of alkaloid precursor feeding on acamptotheca acuminate cell line . Plant physiology and bio –chemistry, 40: 749-753.
- Dmitruk , S.E., .1973. Role of amino acids in the formation of tropane alkaloids , Mter .Obl .Nauchin. Konf-Beca . Khim .O.Va. , posuyashch 1975-letiya Khim –technol Toeusk.poliekh .Ins.3rd 1972 (pub. 1973), pp: 57-59.
- Jain, M. and P. Khanna. 1982. Effect of amino acids on growth and production of atropine in suspension culture of Atropa belladomnna Ind . J. Bot., 5:60 -62.
- Saker ,M.M. and M.R.Rady ,.1997. Elicitation of tropane alkaloids in suspension culture of Hyoscyamus ,Datura and Atropa belladonna by osmotic stress .fitoterapia ,68: 338-342.
- Al-Hattab ,Z. ,N.E.Al-Kateeb, W.K. Al-Quadhy and G.Mahdi. 2000. Effect of growth hormones on tropane alkaloids production in Datura metel.L callus culture .IBN AL-Haitham J.For pure and Appl. Sci.Vol. 12(1).
- Yunus, Awab Waad Allah and Muzahim Qasim Al-Mallah. 2001. Changes in the response of Datura innoxia tissues to tissue culture in three types of nutrient medium, Journal of Education and Science, 3 (6), 44-53.
- Aziz , A ., M . Marziah ,M .Radzali and M.S. Halimi . .2002.The Influence of Precursors on Hyoscyamine and Scopolamine Production by Transformed root Culture of Datura metel Tropical Medicinal plants , 3 (1) :105- 111.
- Mulabagal, l.V., and H . S. Tsay . 2004. Plant cell cultures an alternative and Efficient Source for the Production of Biologically Important Secondary Metabolites . International Journal pf Applied Science and Engineering . 2 , 1: 29 – 48.
- Pua ,E.C.and M.R.Davey ,. 2007.Transgenic crop VI,. PP : 189. springer .Berline , Heidelberg.
- Ibrahim , A .I . ,A.E. K . Mostafa , A. M. Amira and A. E. Asmaa .2009. Alkaloids production and Organogenesis from callus of Hyoscyamus muticus L . In vitro . Journal of Applied sciences Research, 5 (1): 82-92.cairo,Egypt.
- Al-saedi, Noora.j.j.2011.production of some Tropane alkaloids from Atropa belladonna Callus in vitro.A thesis in Horticulture science, College of Agriculture, University of Baghdad.
- Staba,E.J,. 2000.Plant tissue culture as a source of bio chemicals .CRC Press ,Inc .Boca raton ,Florida.pp:1-271.
- Hadi, Sabah Mahdi. 1999. Production of Vinblastine and Vincristine from Callus Cells of Cathranthus roseus using Plant Tissue Culture Technique. Master Thesis. Institute of Biotechnology and Genetic Engineering, University of Baghdad. Pg.: 73.
- Saour, Kawkab Yaqoub, Sabah Mahdi and Ali Sadiq Muhammad. 2000. Detection and quantitative determination of vancastrin in callus cells of Catharanthus roseus, Biotechnology Research Journal, 2 (1): 53-52.
- Iranbakahsh ,A.R.and G.H.Riazi. 2000 . Assay of the time and location of tropane alkaloids biosynthesis in Datura stramonium .pajohesh va sazandegi, 53:82-89.
- Al-Mukhtar, Sarab Abdel-Hadi. 2008. Study of production of some morphine alkaloids from Papaver somniferanm. Outside the living body. Master's thesis, Department of Horticulture - College of Agriculture - University of Baghdad.
- Al-Marsoumi, Haider Emad Rashid. 2010. The effect of the components of the nutrient medium and the cultivated plant part on the formation of callus and the production of some compounds with medicinal uses in the Saliva officinalis plant. Master's thesis, Department of Horticulture - College of Agriculture - University of Baghdad.
- Kamimure , S. and , M .Nishikawa . 1976 . Agricultural and Biological chemistry . 40: 907-11.
- Zenk , M.H.,E.Shgi , H.Arens , H. stockigt , E.W.Weiler , and B.Deus . 1977. Formation of the indole Alkaloids serpentine and ajmalicine in cell Suspension culture of catharathus roseus .InplantTissue culture and its Bio- technological Application , Berlin,New York , PP. 27-43.
- Ballica . R, D. Y. Ryu. 1993 . Tropane Alkaloids production in Datura stramonium Suspension culture :Elicitor and precursor Effect , Biotechnol Bioeng , 41: 1075-1081
- Zabetaki , I., R . Edwared and D .Ohagan ,. 1999. Elicitation of Tropane Alkaloid biosynthesis in transformed root Culture of Datura stramonium . Phytochemistry 50 :53
- Pitta, A , S. I ., T.C. Spollansky, A. M . Giulietti.2000. The Influence of different biotic and abiotic elicitors on production and profile of Tropane alkaloids In hairy root cultures of Brugmansia candida Enzyme microb . Technol . 26:252-258.
- Karam , N. S. ; F .M . Jawad ; N. A. Arikat and R.A.Shibli. 2003. Growth and rosmarinic acid accumlatation In callus , cell suspension and root culture of Salvia fruticosa . Plant cell, tissue and organ Culture , 73 :1-121 .
- Al-Shamaa, Ali Abdul-Hussein. 1989. Drugs and chemistry of medicinal plants, Dar Al-Kutub for printing and publishing
- Al-Ghanmi, Ali Abdul-Kadhim Jassim, 2000. Production, purification and characterization of anti-tumor substances from local sources, PhD thesis, College of Science, University of Baghdad.
- Hart , H . 1983. Organic chemistry .A short course . Sixth edition . Laboratory manual .
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