This study was conducted on Syrian Seed cleaner in talkaief agriculture branch- directorate of agriculture- Nineveh, by using durum wheat grain (om -Rabeaa cultivar) to evaluate the effect of some factors in seed cleaning machine, these factors are: rate of seeds feeding with three levels, (575 , 950 , 1325 kg/h), cyclofan speed with two levels (4.8 m / s) (3.5 m / s), and the angle slope of receiver boat of indent cylinder with three machine slope, (3) , (4) , (5) which equal (50º) , (70º) , (90º) respectively. And their effects on the following traits: Specific weight (kg/Hectoliter)., Percentage of seeds purity %., percentage of seeds germination %. Trying to achieve the best calibration to get the best performance of the seed cleaner and reach the best values for the traies above. Experiment was carried out by using the complete random design (CRD) in factorial experiments, and duncan test at (%5) to test the significant differences between the treatments, the results were as follows :The first level of seeds feeding rate was superior in specific weight and seeds purity, while the second level of seeds feeding rate gave the best results for percentage of germination. The cyclofan speed levels doesn’t affect the studied traits. The first level of angle slope gave highest values for specific weight and the seeds purity% compared with other levels. In triple interaction , the Highest specific weight was recorded at the first level of seed feeding rate and the second level of the cyclofan speed with both second and the third angle slope. The interaction between the first level of seeds feeding rate and second level of cyclofan speed with the first level of the angle slope gave the best results for seeds purity %. while the interaction between the third level of seeds feeding rate and first level of cyclofan speed with the first level of angle slope gave the best result of seeds germination %.